Ipamorelin is a pentapeptide, meaning that it is composed of five amino acids, that mimics the body’s natural GH release. Ipamorelin is a growth hormone releasing peptide (GHRP) and analogue of the hormone Ghrelin. It induces GH release and increases the number of somatarophs(cells responsible for GH release) in a GH pulse by suppressing somatostatin.
Ipamorelin is very similar to the growth hormone releasing peptides (GHRPs) GHRP 2 and GHRP 6 in that it mimics ghrelin (the hunger hormone) and targets a specific HGH pulse. However, unlike other GHRPs, this peptide doesn’t affect the release of cortisol, acetylcholine, prolactin and aldosterone thereby minimizing side effects experienced with other GH therapies, such as increased hunger. Because there are virtually no negative side effects, Ipamorelin can be prescribed more aggressively and more frequently than other therapies without the risk of elevated cortisol and acetylcholine blood plasma levels. This helps optimize HGH levels for a longer period of time, leading to more successful health outcomes.
With virtually no negative side effects, Ipamorelin is one of the safest, most effective forms of growth hormone (GH) restoration, widely used to support age management, disease management, sports performance and GH deficiency treatment protocols.
|Molecular Weight:||711.9 g/mol|
- Hunsinger, Molly. “Peptide Therapy – What Is Ipamorelin and CJC 1295?” Peptide Therapy – What Is Ipamorelin and CJC 1295?, blog.telewellnessmd.com/ipamorelin-and-cjc-1295-peptide-therapy.
- “Ipamorelin.” National Center for Biotechnology Information. PubChem Compound Database, U.S. National Library of Medicine, pubchem.ncbi.nlm.nih.gov/compound/Ipamorelin.